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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9114147 B1

PDFFull Text
Date of Patent:
Aug. 25, 2015

Filed:

Dec. 09, 2013

System and method for diagnosis and treatment

Applicant:

Pop Test Cortisol Llc, Cliffside Park, NJ (US);

Inventors:

Randice Lisa Altschul, Cliffside Park, NJ (US);

Neil David Theise, New York, NY (US);

Myron Rapkin, Indianapolis, IN (US);

Rebecca O'Brien, Shell Knob, MO (US);

Assignee:

Pop Test Oncology Limited Liability Company, Cliffside Park, NJ (US);

Attorney:

Arthur Jacob

Primary Examiner:

Shirley V Gembeh

Int. Cl.
CPC ...
A61K 31/58 (2006.01); A61K 31/337 (2006.01); A61K 31/00 (2006.01); A61K 45/06 (2006.01); C07J 17/00 (2006.01); G01N 33/74 (2006.01); A61N 5/10 (2006.01); A61K 47/10 (2006.01); A61K 47/26 (2006.01); A61K 47/34 (2006.01); A61K 9/08 (2006.01); A61K 9/10 (2006.01); A61K 9/107 (2006.01); A61K 47/42 (2006.01); A61K 47/44 (2006.01); B65D 75/36 (2006.01);
U.S. Cl.
CPC ...
A61K 31/58 (2013.01); A61K 9/08 (2013.01); A61K 9/10 (2013.01); A61K 9/107 (2013.01); A61K 31/00 (2013.01); A61K 31/337 (2013.01); A61K 45/06 (2013.01); A61K 47/10 (2013.01); A61K 47/26 (2013.01); A61K 47/34 (2013.01); A61K 47/42 (2013.01); A61K 47/44 (2013.01); A61N 5/1001 (2013.01); B65D 75/367 (2013.01); C07J 17/00 (2013.01); G01N 33/743 (2013.01); G01N 2800/04 (2013.01); G01N 2800/304 (2013.01); G01N 2800/52 (2013.01); G01N 2800/7004 (2013.01);
Abstract

This invention relates to a low cost rapid response diagnostic system to determine cortisol levels in patients selected as potential candidates for GCR (glucocorticoid receptor) antagonist therapy utilizing a GCR antagonist, such as ORG 34517. The rapid, sensitive, and inexpensive test can be used to determine patients who have non-normal cortisol production or disordered circadian rhythms as a method for selecting subjects for GCR antagonist therapy for whom it is likely to have beneficial and/or therapeutic effects, and can also be used to monitor changes in cortisol levels in response to treatment.

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