The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 18, 2015

Filed:

Jan. 30, 2013
Applicants:

Eugene N. Nikolaev, Moscow, RU;

Roland Jertz, Bremen, DE;

Anton S. Grigoryev, Petropavlovsk-Kamchatsky, RU;

Gökhan Baykut, Bremen, DE;

Inventors:

Eugene N. Nikolaev, Moscow, RU;

Roland Jertz, Bremen, DE;

Anton S. Grigoryev, Petropavlovsk-Kamchatsky, RU;

Gökhan Baykut, Bremen, DE;

Assignee:

Bruker Daltonik GmbH, Bremen, DE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
H01J 49/00 (2006.01);
U.S. Cl.
CPC ...
H01J 49/0036 (2013.01); H01J 49/0027 (2013.01); H01J 49/0031 (2013.01); H01J 2237/223 (2013.01);
Abstract

Fine structures of isotopic peak clusters of substances are determined using ultrahigh resolution mass spectrometry, e.g, FT-ICR mass spectrometry. Resolved individual peaks in the fine structure of the non-monoisotopic peak clusters of organic substances usually contain the additional elemental isotopesC,N,O,O,H,S,S, and combinations thereof. In each of a series of experiments, one of the non-monoisotopic peak clusters is isolated and the corresponding fine structure spectrum acquired. Abundances of the resolved fine structure peaks and their positions on the mass scale are recorded and, after measuring some or all of the isotopic peaks, the atomic composition of the measured substance is calculated. By excluding the monoisotopic peak and isolating only one isotopic peak cluster at a time, the number of ions in the FT-ICR cell is kept low, which avoids resolving power losses due to space charge effects and ion-ion interaction phenomena.


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