The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 18, 2015
Filed:
Nov. 12, 2013
Baxter International Inc., Deerfield, IL (US);
Baxter Healthcare SA, Glattpark, Opifkon, SE;
Katalin Varadi, Vienna, AT;
Hanspeter Rottensteiner, Vienna, AT;
Peter Turecek, Klosterneuburg, AT;
Hans-Peter Schwarz, Vienna, AT;
Jutta Schreiner, Vienna, AT;
BAXALTA INCORPORATED, Bannockburn, IL (US);
BAXALTA GMBH, Glattpark (Opfikon), CH;
Abstract
The invention generally relates to methods of measuring cleaved von Willebrand factor (VWF) fragments. More specifically, the invention relates to methods of measuring the ability of a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13 (ADAMTS13) to cleave VWF in vivo. The invention also relates to methods of using various animal models which demonstrate ADAMTS13 activity similar to that of a human. The invention further relates to methods of measuring the cleavage products of rVWF in mammals, particularly in humans and in human plasma.