The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 18, 2015

Filed:

Jul. 26, 2011
Applicants:

Douglas Steven Baer, Menlo Park, CA (US);

Elena Simone Franklin Berman, Mountain View, CA (US);

Manish Gupta, Mountain View, CA (US);

David A. Wagner, Nashua, NH (US);

Daniel L. Bolt, Medford, MA (US);

Susan Lauren Fortson, Mountain View, CA (US);

Inventors:

Douglas Steven Baer, Menlo Park, CA (US);

Elena Simone Franklin Berman, Mountain View, CA (US);

Manish Gupta, Mountain View, CA (US);

David A. Wagner, Nashua, NH (US);

Daniel L. Bolt, Medford, MA (US);

Susan Lauren Fortson, Mountain View, CA (US);

Assignee:

Los Gatos Research, Mountain View, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/18 (2006.01); G01N 21/31 (2006.01); G01N 21/17 (2006.01); G01N 21/35 (2014.01); G01N 21/39 (2006.01);
U.S. Cl.
CPC ...
G01N 21/31 (2013.01); G01N 21/1702 (2013.01); G01N 2021/3595 (2013.01); G01N 2021/399 (2013.01); Y10T 436/20 (2015.01);
Abstract

Biological fluid samples containing proteins (e.g., blood plasma or saliva) are prepared for isotopic analysis by precipitating the proteins while leaving the isotopic ratio unaffected. This precipitation can involve adding metal ions, salts, organic solvents, or organic polymers. The sample is then centrifuged to allow transfer of the supernatant for isotopic analysis, e.g. by tunable diode laser absorption spectrometry to obtain a quantitative measure of theH andO isotope levels in the water relative to reference standards.


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