The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 18, 2015

Filed:

Jun. 22, 2011
Applicants:

Kengo Takeuchi, Tokyo, JP;

Yuichi Ishikawa, Tokyo, JP;

Hiroyuki Mano, Tochigi, JP;

Manabu Soda, Tochigi, JP;

Eirin Sai, Tochigi, JP;

Inventors:

Kengo Takeuchi, Tokyo, JP;

Yuichi Ishikawa, Tokyo, JP;

Hiroyuki Mano, Tochigi, JP;

Manabu Soda, Tochigi, JP;

Eirin Sai, Tochigi, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); C12P 19/34 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); C12P 19/34 (2013.01); C12Q 1/68 (2013.01); G01N 33/57484 (2013.01); C12Q 2600/156 (2013.01);
Abstract

Polynucleotides which are novel causative genes for cancer are elucidated, and a detection method of the polynucleotides or polypeptides encoded by the polynucleotides, and a kit and a primer set for detection are provided, based on the knowledge gained by the elucidation. In the detection method, a fusion gene comprising part of an SDC4, CD74, EZR, SLC34A2, LRIG3, or TPM3 gene and part of a ROS1 gene, or a fusion protein encoded by the fusion gene is detected. The primer set or the detection kit comprises a sense primer designed based on a portion encoding SDC4, CD74, EZR, SLC34A2, LRIG3, or TPM3 and an antisense primer designed based on a portion encoding ROS1.


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