The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 18, 2015

Filed:

May. 31, 2013
Applicants:

Bavarian Nordic A/s, Kvistgaard, DK;

Otto-von-guericke-universitat Magdeburg, Magdeburg, DE;

Sartorius Stedim Biotech Gmbh, Gottingen, DE;

Inventors:

Sara Post Hansen, Hoersholm, DK;

Rene Faber, Gottingen, DE;

Udo Reichl, Magdeburg, DE;

Michael Wolff, Biederitz, DE;

Anders Peter Gram, Vaerloese, DK;

Assignees:

Bavarian Nordic A/S, Kvistgaard, DK;

Otto-von-Guericke-Universität, Magdeburg, DE;

Sartorius Stedim Biotech GmbH, Göttingen, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 7/01 (2006.01); C12N 7/00 (2006.01); C12N 15/863 (2006.01); C12N 7/02 (2006.01); C12N 15/86 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C12N 7/02 (2013.01); C12N 7/00 (2013.01); C12N 15/86 (2013.01); A61K 2039/5256 (2013.01); C12N 2710/24143 (2013.01); C12N 2710/24151 (2013.01);
Abstract

The present invention relates to methods for purification of Vaccinia viruses (VV) and/or Vaccinia virus (VV) particles, which can lead to highly pure and stable virus preparations of predominantly biologically active viruses. The invention encompasses purifying a virus preparation in a sterilized way with high efficiency and desirable yield in terms of purity, biological activity and stability, aspects advantageous for industrial production.


Find Patent Forward Citations

Loading…