The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 18, 2015

Filed:

May. 24, 2013
Applicants:

The Hong Kong University of Science and Technology, Kowloon, Hong Kong, CN;

National University of Singapore, Singapore, SG;

Inventors:

Benzhong Tang, Hong Kong, CN;

Wing Yip Lam, Hong Kong, CN;

Na Zhao, Hong Kong, CN;

Min Li, Hong Kong, CN;

Bin Liu, Singapore, SG;

Haibin Shi, Singapore, SG;

Dan Ding, Singapore, SG;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 5/00 (2006.01); A61B 8/00 (2006.01); A61B 10/00 (2006.01); C09K 11/06 (2006.01); C12Q 1/37 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
C09K 11/06 (2013.01); C12Q 1/37 (2013.01); A61K 9/0019 (2013.01); G01N 2333/96469 (2013.01);
Abstract

The development of a series of fluorescent materials including heterocycle-functionalized luminogens with aggregation-induced/enhanced emission (AIE/AEE), long wavelength emission, and high solid state fluorescence quantum efficiency is contemplated. The described fluorescent materials are promising candidates in selective luminescence-based chemosensor for Hgor ATP, fluorescent staining for mitochondria in living cells with high photostability, stimuli-responsive luminescent materials, and materials for optical waveguides. In addition, these heterocycle-functionalized luminogens are particularly useful as fluorescent labels for biopolymers such as peptides, antibodies, or nucleic acids, making them useful as AIE-active biocompatible probes for clinical cancer imaging and diagnostics.


Find Patent Forward Citations

Loading…