The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 18, 2015

Filed:

Jul. 13, 2012
Applicants:

Sadayuki Maeda, Kyoto, JP;

Tatsunori Sato, Hyogo, JP;

Yasuhiko Kawano, Osaka, JP;

Toshio Miyawaki, Hyogo, JP;

Inventors:

Sadayuki Maeda, Kyoto, JP;

Tatsunori Sato, Hyogo, JP;

Yasuhiko Kawano, Osaka, JP;

Toshio Miyawaki, Hyogo, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 215/00 (2006.01); C07F 5/00 (2006.01); C07D 215/04 (2006.01); C07B 53/00 (2006.01); C07F 17/02 (2006.01); C07D 215/06 (2006.01); C07D 215/18 (2006.01); C07D 215/20 (2006.01); C07D 215/22 (2006.01); C07D 215/227 (2006.01); C07D 215/14 (2006.01);
U.S. Cl.
CPC ...
C07F 5/00 (2013.01); C07B 53/00 (2013.01); C07D 215/04 (2013.01); C07D 215/06 (2013.01); C07D 215/14 (2013.01); C07D 215/18 (2013.01); C07D 215/20 (2013.01); C07D 215/22 (2013.01); C07D 215/227 (2013.01); C07F 17/02 (2013.01);
Abstract

Provided are a novel chiral iridium(III) complex; and a method for producing optically active 2-substituted-1,2,3,4-tetrahydroquinolines from 2-substituted-quinolines with the use of the chiral iridium(III) complex through a more economical and easy production process. The disclosed method for producing optically active 2-substituted-1,2,3,4-tetrahydroquinolines comprises reducing a quinoline compound represented by formula [I]: in the presence of a hydrogen donor compound and an iridium (III) complex having a chiral prolinamide compound as a ligand to give an optically active 2-substituted-1,2,3,4-tetrahydroquinoline represented by formula [II]:


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