The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 18, 2015
Filed:
Apr. 01, 2010
Applicants:
Kazutoshi Watanabe, Tokyo, JP;
Kazuki Nakayama, Kanagawa, JP;
Daiki Sakai, Kanagawa, JP;
Inventors:
Assignee:
MITSUBISHI TANABE PHARMA CORPORATION, Osaka, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/553 (2006.01); C07D 401/14 (2006.01); C07D 403/14 (2006.01); C07D 413/14 (2006.01);
U.S. Cl.
CPC ...
C07D 413/14 (2013.01); C07D 401/14 (2013.01); C07D 403/14 (2013.01);
Abstract
A compound represented by the formula (I) or a pharmaceutically acceptable salt thereof: wherein Z represents nitrogen atom, C—F or the like; Rrepresents a C-Calkyl group;Y represents oxygen atom or N—R; R, R, R, R, Rand Reach independently represents hydrogen atom, a C-Calkyl group, or a group represented by the formula (II): which is used for preventive and/or therapeutic treatment of a disease caused by tau protein kinase 1 hyperactivity such as a neurodegenerative diseases (e.g. Alzheimer disease).