The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9108930 B1

PDF
Full Text
Expired
Date of Patent:
Aug. 18, 2015

Filed:

Apr. 05, 2012
Applicants:

Benjamin Cravatt, La Jolla, CA (US);

Alexander Adibekian, Hanover, DE;

Katsunori Tsuboi, Osaka, JP;

Ku-lung Hsu, El Cajon, CA (US);

Inventors:

Benjamin Cravatt, La Jolla, CA (US);

Alexander Adibekian, Hanover, DE;

Katsunori Tsuboi, Osaka, JP;

Ku-Lung Hsu, El Cajon, CA (US);

Assignee:

The Scripps Research Institute, La Jolla, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 249/06 (2006.01); C07D 401/08 (2006.01); C07D 249/04 (2006.01); C07D 401/06 (2006.01); C07D 403/06 (2006.01); C07D 471/04 (2006.01); C07D 495/04 (2006.01); C07F 5/02 (2006.01);
U.S. Cl.
CPC ...
C07D 249/04 (2013.01); C07D 249/06 (2013.01); C07D 401/06 (2013.01); C07D 403/06 (2013.01); C07D 471/04 (2013.01); C07D 495/04 (2013.01); C07F 5/022 (2013.01);
Abstract

The present invention provides inhibitors of a wide variety of serine hydrolase enzymes. The inhibitors of the present invention are N1- and N2-carbamoyl-1,2,3-triazole compounds such as those of Formula (I): in which N1, N2, and N3 are the nitrogen atoms at positions 1, 2, and 3, respectively, of the triazole ring, and R, R, Rand Rin Formula (I) are as described herein. Methods of inhibiting serine hydrolase enzymes and methods of preparing carbamoyl-1,2,3-triazole compounds also are described.


Find Patent Forward Citations

Cravatt, Benjamin. (2015). N1- and n2-carbamoyl-1,2,3-triazole serine hydrolase inhibitors and methods (U.S. Patent No. 9108930). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9108930

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