The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 18, 2015
Filed:
Sep. 20, 2012
Applicant:
Fresenius Kabi Oncology Limited, New Delhi, IN;
Inventors:
Bhuwan Bhaskar Mishra, Haryana, IN;
Nikunj Shambhubhai Kachhadia, Haryana, IN;
Vinod Singh Tomar, Haryana, IN;
Saswata Lahiri, Haryana, IN;
Assignee:
Fresenius Kabi Oncology Limited, New Delhi, IN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 235/16 (2006.01);
U.S. Cl.
CPC ...
C07D 235/16 (2013.01);
Abstract
The present invention relates to an improved process for the synthesis of bendamustine, in particular, bendamustine hydrochloride of the formula (VI) and its intermediate 1-methyl-5-[bis(2-chloroethyl)amino]-1H-benzimidazol-2-yl]lithium butanoate of formula (V), both having a purity of ≧99%, which is simple, convenient, economical, does not use hazardous chemicals and is industrially viable.