The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 18, 2015

Filed:

Jan. 25, 2010
Applicants:

Keizo Koya, Chestnut Hill, MA (US);

Lijun Sun, Harvard, MA (US);

Shoujun Chen, Bedford, MA (US);

Noriaki Tatsuta, Lexington, MA (US);

Yaming Wu, Lexington, MA (US);

Mitsunori Ono, Lexington, MA (US);

Inventors:

Keizo Koya, Chestnut Hill, MA (US);

Lijun Sun, Harvard, MA (US);

Shoujun Chen, Bedford, MA (US);

Noriaki Tatsuta, Lexington, MA (US);

Yaming Wu, Lexington, MA (US);

Mitsunori Ono, Lexington, MA (US);

Assignee:

Synta Pharmaceuticals Corp., Lexington, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/16 (2006.01); A61K 31/165 (2006.01); A61K 47/48 (2006.01); A61K 31/381 (2006.01); A61K 31/277 (2006.01); A61K 31/337 (2006.01); A61K 31/44 (2006.01); A61K 31/505 (2006.01); A61K 31/53 (2006.01); C07C 327/56 (2006.01); C07D 209/42 (2006.01); C07D 209/44 (2006.01); C07D 213/83 (2006.01); C07D 261/18 (2006.01); C07D 305/14 (2006.01); C07D 307/68 (2006.01); C07D 333/38 (2006.01); C07D 333/68 (2006.01); C07D 407/12 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48176 (2013.01); A61K 31/16 (2013.01); A61K 31/165 (2013.01); A61K 31/277 (2013.01); A61K 31/337 (2013.01); A61K 31/381 (2013.01); A61K 31/44 (2013.01); A61K 31/505 (2013.01); A61K 31/53 (2013.01); C07C 327/56 (2013.01); C07D 209/42 (2013.01); C07D 209/44 (2013.01); C07D 213/83 (2013.01); C07D 261/18 (2013.01); C07D 305/14 (2013.01); C07D 307/68 (2013.01); C07D 333/38 (2013.01); C07D 333/68 (2013.01); C07D 407/12 (2013.01); C07C 2101/02 (2013.01); C07C 2101/04 (2013.01); C07C 2101/08 (2013.01); C07C 2101/14 (2013.01);
Abstract

Disclosed is a compound represented by the Structural Formula (I): Also disclosed are pharmaceutical compositions comprising the compound of the present invention and a pharmaceutically acceptable carrier or diluent. Also disclosed is a method of treating a subject with cancer by administering to the subject a compound of Structural Formula (I) in combination with Paclitaxel or an analog of Paclitaxel.


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