The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 18, 2015
Filed:
Jan. 05, 2010
Applicants:
Victoria Smith, Burlingame, CA (US);
Alison Kay Holzer, Redwood City, CA (US);
Inventors:
Victoria Smith, Burlingame, CA (US);
Alison Kay Holzer, Redwood City, CA (US);
Assignee:
Gilead Biologics, Inc., Foster City, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 48/00 (2006.01); C12N 15/113 (2010.01); C07K 16/00 (2006.01); A61K 31/7105 (2006.01); A61K 31/282 (2006.01); A61K 31/337 (2006.01); A61K 31/513 (2006.01); A61K 31/517 (2006.01); A61K 31/519 (2006.01); A61K 31/704 (2006.01); A61K 31/7068 (2006.01); A61K 33/24 (2006.01); A61K 45/06 (2006.01); C07K 16/40 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7105 (2013.01); A61K 31/282 (2013.01); A61K 31/337 (2013.01); A61K 31/513 (2013.01); A61K 31/517 (2013.01); A61K 31/519 (2013.01); A61K 31/704 (2013.01); A61K 31/7068 (2013.01); A61K 33/24 (2013.01); A61K 39/3955 (2013.01); A61K 45/06 (2013.01); C07K 16/40 (2013.01); C12N 15/1137 (2013.01); C12N 2310/14 (2013.01);
Abstract
Disclosed herein are methods and compositions for enhancing the cell-killing activity of anti-neoplastic agents by inhibiting the activity of a lysyl oxidase-type enzyme. Also disclosed are methods for screening for chemotherapeutic agents, and for molecules that enhance the activity of chemotherapeutic agents, using cells grown on an extracellular matrix.