The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 18, 2015

Filed:

Jun. 03, 2014
Applicant:

Universite Catholique DE Louvain, Louvain-la-Neuve, BE;

Inventors:

Etienne Sokal, Hoeilaart, BE;

Mustapha Najimi, Woluwe Saint-Lambert, BE;

Assignee:

UNIVERSITÉ CATHOLIQUE DE LOUVAIN, Louvain-la-Neuve, BE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/074 (2010.01); C12N 5/071 (2010.01); A61K 48/00 (2006.01); C12N 15/00 (2006.01); A61K 35/407 (2015.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
A61K 35/407 (2013.01); C12N 5/0672 (2013.01); G01N 33/5067 (2013.01);
Abstract

Isolated liver progenitor stem cells and cell populations of isolated liver progenitor stem cells are disclosed. The progenitor stem cells originate from adult liver, especially human adult liver. The isolated progenitor stem cells have uses in medicine, hepatology, inborn errors of liver metabolism transplantation, infectious diseases and liver failure. Methods of isolating these cells and their culture is described. The isolated cells are characterized before and after differentiation. Their use for transplantation and as animal models of human disease, toxicology and pharmacology is disclosed.


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