The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 18, 2015

Filed:

Feb. 11, 2013
Applicant:

The Board of Trustees of the University of Illinois, Urbana, IL (US);

Inventors:

Rajeshwari R Mehta, Orland Park, IL (US);

Brad N Taylor, Chicago, IL (US);

Tohru Yamada, Oak Park, IL (US);

Craig W Beattie, Chicago, IL (US);

Tapas K Das Gupta, River Forest, IL (US);

Ananda M Chakrabarty, Villa Park, IL (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 49/00 (2006.01); A61K 39/00 (2006.01); A61K 39/02 (2006.01); A61K 38/16 (2006.01); A01K 67/027 (2006.01); A61K 45/06 (2006.01); C07K 14/21 (2006.01); G01N 33/68 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/164 (2013.01); A01K 67/0271 (2013.01); A61K 45/06 (2013.01); C07K 14/21 (2013.01); G01N 33/6893 (2013.01); A01K 2207/15 (2013.01); A01K 2227/105 (2013.01); A01K 2267/0331 (2013.01); A61K 38/00 (2013.01);
Abstract

The present invention relates to compositions comprising cupredoxins, and their use to inhibit angiogenesis in mammalian cells, tissues, and animals, and particularly the angiogenesis that accompanies tumor development and particularly in humans. Specifically, the present invention relates to compositions comprising the cupredoxin(s), and or peptides that are variants, derivatives or structural equivalents of cupredoxins, which retain the ability to inhibit angiogenesis in mammalian cells, tissues or animals. These compositions may be peptides or pharmaceutical compositions, among others. The compositions of the invention may be used to treat any pathological condition that has as a symptom or cause, inappropriate angiogenesis, and particularly inappropriate angiogenesis related to tumor development.


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