The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 18, 2015
Filed:
Apr. 01, 2011
Joseph Parello, Nashville, TN (US);
Keya Bandyopadhyay, San Diego, CA (US);
Jean-louis Baneres, Montpellier, FR;
Casimir Blonski, Villebon-sur-Yvette, FR;
Ruth Anne Gjerset, San Diego, CA (US);
Aimee Martin, Montpellier, FR;
Joseph Parello, Nashville, TN (US);
Keya Bandyopadhyay, San Diego, CA (US);
Jean-Louis Baneres, Montpellier, FR;
Casimir Blonski, Villebon-sur-Yvette, FR;
Ruth Anne Gjerset, San Diego, CA (US);
Aimee Martin, Montpellier, FR;
Vanderbilt University, Nashville, TN (US);
Abstract
A method of treating cancer in a subject in need thereof, comprising administering to the subject a first amount of a compound of the HAT inhibitor of the following formula: wherein R is chosen from coenzyme A, (CH)NHCO(CH)NHCOR; (CH)NHCOR; (CH)NHCO(CH)NHCOR; Ris H, NH, NH, N, and Rcan optionally cyclize with at least one other Xto form a Cmembered ring containing C, O, S, or N; Ris chosen from alkyl, cycloalkyl, aryl, heteroaryl; Ris chosen from an alkyl, cycloalkyl, aryl, heteroaryl; Ris chosen from CH(OH)C(CH)CH)OCOR; Xis chosen from H or can cyclize with one other Xor Rto form a Cmembered ring containing C, O, S, or N; and Xis chosen from C, N, NH, and can optionally cyclize with at least one other Xor Rto form a Cmembered ring containing C, O, S, or N; or a pharmaceutically acceptable salt or hydrate thereof, thereby treating the cancer.