The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 18, 2015
Filed:
Apr. 06, 2011
Applicant:
John W. Holaday, Bethesda, MD (US);
Inventor:
John W. Holaday, Bethesda, MD (US);
Assignee:
EXOCYTE THERAPEUTICS PTE, LTD, Singapore, SG;
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/14 (2015.01); A61K 39/00 (2006.01); A61K 35/15 (2015.01); A61K 35/13 (2015.01);
U.S. Cl.
CPC ...
A61K 35/15 (2013.01); A61K 35/13 (2013.01); A61K 39/0011 (2013.01); A61K 2039/5154 (2013.01); A61K 2039/5158 (2013.01);
Abstract
The present invention relates to compositions and methods for treating an animal with a tumor or other metabolic disorder. In particular, the presently disclosed subject matter relates to methods of electroporating exosomes shed by tumors and by other metabolic disorders into immune cells such as dendritic cells and T cells. Administration of the electroporated immune cells to an animal with a tumor results in an increased immune response to the tumor and treatment of the tumor.