The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 18, 2015

Filed:

Jan. 11, 2007
Applicants:

Stephen J Savarino, Kensington, MD (US);

Randall K Holmes, Golden, CO (US);

Michael G Jobling, Aurora, CO (US);

Inventors:

Stephen J Savarino, Kensington, MD (US);

Randall K Holmes, Golden, CO (US);

Michael G Jobling, Aurora, CO (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/02 (2006.01); A61K 39/108 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0258 (2013.01); A61K 2039/522 (2013.01); A61K 2039/523 (2013.01); A61K 2039/54 (2013.01); A61K 2039/543 (2013.01); A61K 2039/545 (2013.01); A61K 2039/6037 (2013.01); A61K 2039/627 (2013.01);
Abstract

The inventive subject matter relates to an immunogenic composition composed of a chimeric molecule including a conformationally stable adhesin fromfused to a bacterial toxin A subunit, such as cholera toxin A subunit or heat-labiletoxin A subunit. The invention also relates to the adhesin-toxin chimera noncovalently associated with a toxin B subunit of the same or different species as the A subunit. The invention also relates to a method of utilizing an adhesin/toxin fusion composition to elicit an immune response.


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