The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 18, 2015
Filed:
Dec. 05, 2007
Applicants:
Ferencz S. Denes, Madison, WI (US);
Zsuzsanna Fabry, Madison, WI (US);
Matyas Sandor, Madison, WI (US);
Inventors:
Ferencz S. Denes, Madison, WI (US);
Zsuzsanna Fabry, Madison, WI (US);
Matyas Sandor, Madison, WI (US);
Assignee:
Wisconsin Alumni Research Foundation, Madison, WI (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/38 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
A61K 39/00 (2013.01); A61K 39/0005 (2013.01); A61K 2039/5154 (2013.01); C07K 16/28 (2013.01);
Abstract
The present invention provides compositions and methods for targeting dendritic cells of the immune system. In particular, the compositions comprise carbon nanoparticles, optionally magnetic carbon nanoparticles comprising iron, which are preferentially endocytosed by dendritic cells compared to macrophages when contacted with a biological sample. The nanoparticles of the present invention may be functionalized to enhance delivery of biomolecules to dendritic cells.