The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 11, 2015
Filed:
May. 12, 2010
Applicants:
Olivier DE Wever, Oostende, BE;
An Hendrix, Mol, BE;
Wendy Westbroek, Rockville, MD (US);
Inventors:
Assignee:
Universiteit Gent, Ghent, BE;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C12Q 1/68 (2006.01); G01N 33/574 (2006.01); C07K 14/82 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
G01N 33/57415 (2013.01); C07K 14/82 (2013.01); C12N 15/1135 (2013.01); C12N 2310/14 (2013.01); G01N 2333/4719 (2013.01);
Abstract
The present invention relates to evaluating the prognosis of patients with estrogen receptor-positive breast cancer on the basis of Rab27B expression. The invention further relates to a kit comprising an assay for measuring Rab27B levels in said patients and to the usage of Rab27B as a target to screen for drugs capable of inhibiting or diminishing metastasis of said cancer. Furthermore, the invention discloses compounds which can be used to treat estrogen receptor-positive breast cancer.