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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9103814 B1

PDFFull Text
Date of Patent:
Aug. 11, 2015

Filed:

Mar. 16, 2007

Solvent delivery system for liquid chromatography that maintains fluid integrity and pre-forms gradients

Applicants:

Steven J. Ciavarini, Natick, MA (US);

Stanley P. Pensak, Jr., East Walpole, MA (US);

Jeffrey W. Finch, Gig Harbor, WA (US);

Keith Fadgen, Hope Valley, RI (US);

Hongji Liu, Grafton, MA (US);

Inventors:

Steven J. Ciavarini, Natick, MA (US);

Stanley P. Pensak, Jr., East Walpole, MA (US);

Jeffrey W. Finch, Gig Harbor, WA (US);

Keith Fadgen, Hope Valley, RI (US);

Hongji Liu, Grafton, MA (US);

Assignee:

Waters Technologies Corporation, Milford, MA (US);

Attorneys:

Locke Lord LLP

Nicholas J. DiCeglie, Jr.

Primary Examiner:

Ernest G Therkorn

Int. Cl.
CPC ...
G01N 30/34 (2006.01);
U.S. Cl.
CPC ...
G01N 30/34 (2013.01);
Abstract

A solvent delivery subsystem for a chromatography device performs relatively low pressure, high flow mixing of solvents to form a gradient and subsequent high pressure, low flow delivery of the gradient to the separation column. The mixing of the gradient is independent and does not interfere with the gradient delivery. To form the gradient, the outputs of an aqueous pump and an organic pump are mixed to fill a storage capillary while a downstream point from the storage capillary is vented to atmosphere. After gradient formation, the vent to atmosphere is closed, the solvent delivery system rises to high pressure, and only the aqueous pump runs for gradient delivery. To maintain integrity of the fluid stream, the solvent delivery system uses feed forward compensation and controls at least one parameter selected from the group consisting of pressure and flow in the conduit means to follow a gradual ramp.

Find Patent Forward Citations

Ciavarini, Steven. (2015). Solvent delivery system for liquid chromatography that maintains fluid integrity and pre-forms gradients (U.S. Patent No. 9103814). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9103814

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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