The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 11, 2015
Filed:
Apr. 16, 2009
Keith A. Bauer, San Rafael, CA (US);
Ellen Fiss, Albany, CA (US);
David H. Gelfand, Oakland, CA (US);
Edward S. Smith, San Francisco, CA (US);
Shawn Suko, El Sobrante, CA (US);
Olga Budker, El Cerrito, CA (US);
Nancy Schoenbrunner, Moraga, CA (US);
Susanne Stoffel, El Cerrito, CA (US);
Thomas Myers, Los Altos, CA (US);
Keith A. Bauer, San Rafael, CA (US);
Ellen Fiss, Albany, CA (US);
David H. Gelfand, Oakland, CA (US);
Edward S. Smith, San Francisco, CA (US);
Shawn Suko, El Sobrante, CA (US);
Olga Budker, El Cerrito, CA (US);
Nancy Schoenbrunner, Moraga, CA (US);
Susanne Stoffel, El Cerrito, CA (US);
Thomas Myers, Los Altos, CA (US);
Roche Molecular Systems, Inc., Pleasanton, CA (US);
Abstract
Disclosed are mutant DNA polymerases having improved extension rates relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. The mutant polymerases overcome the inhibitory effects by an intercalating dye. Therefore, the mutant polymerases are useful in a variety of disclosed methods in combination with an intercalating dye. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.