The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 11, 2015

Filed:

Mar. 15, 2013
Applicant:

Medivas, Llc, San Diego, CA (US);

Inventors:

Zaza D. Gomurashvili, La Jolla, CA (US);

Jonathan Macferran Hughes, Carlsbad, CA (US);

Jie Da, San Diego, CA (US);

Huashi Zhang, San Diego, CA (US);

Assignee:

MEDIVAS, LLC, San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C08L 77/12 (2006.01); A61L 31/04 (2006.01); A61L 31/06 (2006.01); A61L 31/14 (2006.01); C08G 69/44 (2006.01);
U.S. Cl.
CPC ...
C08L 77/12 (2013.01); A61L 31/041 (2013.01); A61L 31/06 (2013.01); A61L 31/148 (2013.01); C08G 69/44 (2013.01);
Abstract

The present invention provides biodegradable, biocompatible bis-(α-amino acyl)-diol-diester-containing poly(ester amide) (PEA) and poly(ester urethane) (PEUR) co-polymer compositions with mechanical properties that can be readily tailored by selection of various combinations and proportions of the building blocks of the co-polymers. The compositions are suitable for use in production of drug-releasing biodegradable particles and implantable surgical devices, such as stents and internal fixation devices. The co-polymer compositions, particles and surgical devices biodegrade in vivo by enzymatic action to release bioactive agents in a controlled manner over time as well as biocompatible breakdown products, including one to multiple different amino acids.


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