The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 11, 2015
Filed:
Jun. 24, 2011
Jerzy Szczepan Pieczykolan, Radecznica, PL;
Sebastian Pawlak, Warsaw, PL;
Bartlomiej Zerek, Dabrowa, PL;
Krzysztof Kazimierz Lemke, Gdynia, PL;
Jerzy Szczepan Pieczykolan, Radecznica, PL;
Sebastian Pawlak, Warsaw, PL;
Bartlomiej Zerek, Dabrowa, PL;
Krzysztof Kazimierz Lemke, Gdynia, PL;
ADAMED SP. Z O.O., Czosnow k/Warszawy, PL;
Abstract
The fusion protein, especially recombinant, comprising domain (a) which is a functional fragment of soluble hTRAIL protein sequence beginning with an amino acid at a position not lower than hTRAIL95 or a sequence having at least 70% homology thereto; and domain (b) which is a sequence of pro-apoptotic effector peptide, wherein the sequence of domain (b) is attached at C-terminus and/or N-terminus of domain (a). The fusion protein has anticancer activity. The nucleotide sequence coding the fusion protein, expression vector and host cell for the preparation of the fusion protein, and the use of the fusion protein for treating cancer diseases.