The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 11, 2015

Filed:

Jan. 18, 2011
Applicants:

Balasingam Radhakrishnan, Chapel Hill, NC (US);

Diti Aggarwal, Raleigh, NC (US);

Michelle Ferro, Raleigh, NC (US);

Kenneth D. James, Mebane, NC (US);

Navdeep B. Malkar, Cary, NC (US);

Mark A. Miller, Raleigh, NC (US);

Monica E. Puskas, Spring Hope, NC (US);

Nnochiri N. Ekwuribe, Cary, NC (US);

Inventors:

Balasingam Radhakrishnan, Chapel Hill, NC (US);

Diti Aggarwal, Raleigh, NC (US);

Michelle Ferro, Raleigh, NC (US);

Kenneth D. James, Mebane, NC (US);

Navdeep B. Malkar, Cary, NC (US);

Mark A. Miller, Raleigh, NC (US);

Monica E. Puskas, Spring Hope, NC (US);

Nnochiri N. Ekwuribe, Cary, NC (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/62 (2006.01); A61K 9/00 (2006.01); A61K 9/20 (2006.01); A61K 33/30 (2006.01); A61K 45/06 (2006.01); A61K 47/48 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/62 (2013.01); A61K 9/0095 (2013.01); A61K 9/2013 (2013.01); A61K 9/2018 (2013.01); A61K 33/30 (2013.01); A61K 45/06 (2013.01); A61K 47/48215 (2013.01); A61K 47/48769 (2013.01); A61K 38/00 (2013.01);
Abstract

An insulin conjugate is disclosed in which insulin is coupled to a modifying moiety of the formula X—R—Y-PAG-Z—Rwherein X, Y, and Z are linking groups, Ris a capping group, and PAG is a carbon chain that incorporates one or more alkylene glycol moieties.


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