The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9102667 B1

PDF
Full Text
Expired
Date of Patent:
Aug. 11, 2015

Filed:

Jan. 18, 2012
Applicants:

Enno Klussmann, Berlin, DE;

Walter Rosenthal, Kleinmachnow, DE;

Jelena Milic, Berlin, DE;

Martin W. Bergmann, Hamburg, DE;

Inventors:

Enno Klussmann, Berlin, DE;

Walter Rosenthal, Kleinmachnow, DE;

Jelena Milic, Berlin, DE;

Martin W. Bergmann, Hamburg, DE;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 417/12 (2006.01); C07D 403/12 (2006.01); C07D 413/12 (2006.01); A61K 31/135 (2006.01); A61K 31/343 (2006.01); A61K 31/381 (2006.01); A61K 31/428 (2006.01); A61K 31/4402 (2006.01); A61K 31/4406 (2006.01); A61K 31/4427 (2006.01); A61K 31/47 (2006.01); A61K 31/4709 (2006.01); C07D 333/64 (2006.01); C07D 409/12 (2006.01);
U.S. Cl.
CPC ...
C07D 417/12 (2013.01); A61K 31/135 (2013.01); A61K 31/343 (2013.01); A61K 31/381 (2013.01); A61K 31/428 (2013.01); A61K 31/4402 (2013.01); A61K 31/4406 (2013.01); A61K 31/4427 (2013.01); A61K 31/47 (2013.01); A61K 31/4709 (2013.01); C07D 333/64 (2013.01); C07D 403/12 (2013.01); C07D 409/12 (2013.01); C07D 413/12 (2013.01);
Abstract

The invention relates to N-arylaminomethylenebenzothiophenones of General Formula (I) for use as a drug for the treatment of cardiovascular diseases: wherein E is S, O, or CH, D is CH or NH, and Ar is a phenyl or naphtyl moiety substituted by an electron-withdrawing group, an unsubstituted heteroaryl residue, or a heteroaryl residue substituted by alkyl or an electron-withdrawing group.


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