The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 11, 2015
Filed:
Aug. 22, 2011
Applicants:
Daria Mochly-rosen, Menlo Park, CA (US);
Che-hong Chen, Fremont, CA (US);
Xiaohu Ouyang, Fremont, CA (US);
Inventors:
Daria Mochly-Rosen, Menlo Park, CA (US);
Che-Hong Chen, Fremont, CA (US);
Xiaohu Ouyang, Fremont, CA (US);
Assignee:
The Board of Trustees-Leland Stanford Junior University, Palo Alto, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 317/44 (2006.01); A01N 43/30 (2006.01); A61K 31/36 (2006.01); C07D 405/00 (2006.01); C07D 317/58 (2006.01); C07D 405/12 (2006.01);
U.S. Cl.
CPC ...
C07D 317/58 (2013.01); C07D 405/12 (2013.01);
Abstract
The present invention provides compounds that function as modulators of mitochondrial aldehyde dehydrogenase-2 (ALDH2) activity; and pharmaceutical compositions comprising the compounds. The present invention provides therapeutic methods involving administering a subject compound, or a subject pharmaceutical composition. The present invention further provides assays for identifying agonists of ALDH2.