The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 11, 2015
Filed:
May. 22, 2013
Carna Biosciences Inc., Kobe, Hyogo, JP;
National Cancer Center, Tokyo, JP;
Masaaki Sawa, Ibaraki, JP;
Hideki Moriyama, Kobe, JP;
Tesshi Yamada, Tokyo, JP;
Miki Shitashige, Tokyo, JP;
Yusuke Kawase, Ashiya, JP;
Yuko Uno, Kobe, JP;
CARNA BIOSCIENCES, INC., Kobe-shi, JP;
NATIONAL CANCER CENTER, Tokyo, JP;
Abstract
The present invention relates to novel bicyclic thiazole compounds that inhibit Traf2- and Nck-interacting kinase (TNIK), and as such are useful as TNIK inhibitors administered to cancer patients, especially to solid cancer patients such as colorectal cancer, pancreatic cancer, non-small cell lung cancer, prostate cancer or breast cancer. The bicyclic thiazole compounds are showed by a next formula (I). (wherein R, R, Rand Q are as defined in the specification), or a pharmaceutically acceptable salt thereof.