The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 11, 2015
Filed:
Nov. 03, 2011
Applicants:
Lennart Mucke, San Francisco, CA (US);
Moustapha Cisse, San Francisco, CA (US);
Inventors:
Lennart Mucke, San Francisco, CA (US);
Moustapha Cisse, San Francisco, CA (US);
Assignee:
THE J. DAVID GLADSTONE INSTITUTES, San Francisco, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); A61K 31/7088 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
A61K 31/7088 (2013.01); A61K 48/005 (2013.01); G01N 33/6896 (2013.01); C12N 2799/027 (2013.01); G01N 2333/4709 (2013.01); G01N 2500/02 (2013.01); G01N 2500/10 (2013.01);
Abstract
The present disclosure provides a method of increasing the level and/or function of an Eph receptor B2 in a neuronal cell; and methods of treating an amyloid-beta-induced neurodegenerative disease in an individual. The present disclosure further provides methods of identifying an agent that increases the level and/or function of an Eph receptor B2 in a neuronal cell.