The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 11, 2015
Filed:
Jan. 03, 2013
The United States of America, As Represented BY the Secretary, Department of Health and Human Service, Washington, DC (US);
Leonard M. Neckers, Bethesda, MD (US);
Carole A.C. Sourbier, Rockville, MD (US);
W. Marston Linehan, North Bethesda, MD (US);
Jane B. Neckers, Bethesda, MD (US);
Min-Jung Lee, North Potomac, MD (US);
Bradley T. Scroggins, Rockville, MD (US);
John A. Beutler, Union Bridge, MD (US);
Abstract
Disclosed are methods of treating an animal for insulin resistance and associated diseases or conditions, activating the transcriptional activity of heat shock factor 1 (HSF1), or inducing the expression of heat shock protein 70 (HSP70) in an animal in need thereof, wherein the methods involve administering an effective amount of one or more compounds of formula (I) or an epimer thereof, wherein Ar, and R-Rare described herein. Examples of diseases or conditions associated with insulin resistance include diabetes, obesity, inflammation, metabolic syndrome, polycystic ovary disease, arteriosclerosis, non-alcoholic fatty liver disease, reproductive abnormality in a female, and growth abnormality.