The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 11, 2015
Filed:
Jun. 25, 2010
Daisuke Fujiwara, Yokohama, JP;
Masaru Kato, Yokohama, JP;
Hideki Koizumi, Yokohama, JP;
Kumiko Ikado, Yokohama, JP;
Yasuhisa Ano, Yokohama, JP;
Daisuke Fujiwara, Yokohama, JP;
Masaru Kato, Yokohama, JP;
Hideki Koizumi, Yokohama, JP;
Kumiko Ikado, Yokohama, JP;
Yasuhisa Ano, Yokohama, JP;
KIRIN HOLDINGS KABUSHIKI KAISHA, Tokyo, JP;
Abstract
The present invention provides dendritic cells (DCs) having reduced inflammatory activity, a method for producing DCs capable of inducing regulatory T cells and regulatory T cells, and substances useful for such a method, wherein the DCs and regulatory T cells are useful for prevention and treatment of immune diseases. The present invention relates to a cereal plant-derived material fermented with a koji microorganism, which is obtained by fermentation thereof with a koji microorganism, or a processed product thereof. Preferably, the fermented product or a processed product thereof comprises 14-dehydroergosterol. According to the present invention, regulatory DCs and regulatory T cells can be induced and the proliferation of inflammatory T cells can be suppressed using plant-derived materials.