The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 11, 2015
Filed:
May. 10, 2010
Applicants:
Iannis Aifantis, Brooklyn, NY (US);
Silvia Buonamici, Boston, MA (US);
Inventors:
Iannis Aifantis, Brooklyn, NY (US);
Silvia Buonamici, Boston, MA (US);
Assignee:
New York University, New York, NY (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/02 (2006.01); A61K 31/00 (2006.01); A61K 31/439 (2006.01); A61K 31/519 (2006.01); A61K 31/704 (2006.01); G01N 33/50 (2006.01); A61K 31/573 (2006.01); A61K 31/7068 (2006.01); A61K 31/7088 (2006.01); A61K 38/50 (2006.01); A61K 45/06 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
A61K 38/02 (2013.01); A61K 31/00 (2013.01); A61K 31/439 (2013.01); A61K 31/519 (2013.01); A61K 31/573 (2013.01); A61K 31/704 (2013.01); A61K 31/7068 (2013.01); A61K 31/7088 (2013.01); A61K 38/50 (2013.01); A61K 45/06 (2013.01); G01N 33/5041 (2013.01); G01N 33/57426 (2013.01); G01N 2500/10 (2013.01);
Abstract
The present invention is directed to methods of preventing central nervous system leukemia, treating T-cell acute lymphoblastic leukemia, and treating immune system disorders associated with CCR7-CCL19 mediated signaling. Suitable therapeutic agents for inhibiting CCR7-CCL19 signaling and methods of identifying additional therapeutic agents useful in the methods of the present invention are also disclosed.