The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 04, 2015

Filed:

Oct. 08, 2009
Applicants:

Jung Bum Choi, Cheongju-si, KR;

Jong Jin Lee, Cheongju-si, KR;

Inventors:

Jung Bum Choi, Cheongju-si, KR;

Jong Jin Lee, Cheongju-si, KR;

Assignee:

NanoChips, Inc., Cheongju-si, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 27/00 (2006.01); G01N 33/58 (2006.01); B82Y 15/00 (2011.01); C12Q 1/68 (2006.01); G01N 33/487 (2006.01); B82Y 5/00 (2011.01); B01L 3/00 (2006.01); G01N 27/414 (2006.01);
U.S. Cl.
CPC ...
G01N 33/588 (2013.01); B82Y 15/00 (2013.01); C12Q 1/6869 (2013.01); G01N 33/48721 (2013.01); B01L 3/502761 (2013.01); B82Y 5/00 (2013.01); G01N 27/00 (2013.01); G01N 27/414 (2013.01); Y10S 436/806 (2013.01);
Abstract

The present system relates to a system architecture that uses a single electron transistor (SET) to analyze base sequences of deoxyribonucleic acid (DNA) at ultra high speed in real time. DNA represents the entire body of genetic information and consists of nucleotide units. There are a total of four types of nucleotides, and each nucleotide consists of an identical pentose (deoxyribose), phosphate group, and one of four types of bases (Adenine: A, Guanine: G, Cytosine: C, Thymine: T). A and G are purines having a bicyclic structure while C and T are pyrimidines having a monocyclic structure. Each has a different atomic arrangement, which signifies a different charge distribution from one another. Therefore, a system comprising a single electron transistor that is very sensitive to charges, a probe of a very small size that reacts to one nucleotide very effectively, and an extended gate that connects the SET with the probe, can be used to analyze DNA base sequences at ultra high speed in real time.


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