The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 04, 2015

Filed:

Jul. 12, 2013
Applicant:

Hologic, Inc., Marlborough, MA (US);

Inventors:

Hatim T. Allawi, Middleton, WI (US);

Victor I. Lyamichev, Madison, WI (US);

Assignee:

HOLOGIC, INC., Bedford, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6832 (2013.01); C12Q 1/6823 (2013.01); C12Q 1/6827 (2013.01); C12Q 1/6851 (2013.01);
Abstract

The present invention provides systems, methods and kits for performing a detection assay (e.g., invasive cleavage assay) in combination with an amplification assay (e.g., PCR), where the detection assay employs enzyme footprint probes with relatively short (e.g., 6-12 bases) analyte-specific regions configured to provide a preferred footprint length of duplex for use with a particular nucleic acid modifying enzyme. In some embodiments, such assays are used for target quantification, and in other embodiments, such assays are used for genotyping. In certain embodiments, the use of such short probes allows for assays with increased dynamic range.


Find Patent Forward Citations

Allawi, Hatim. (2015). Methods for analysis of nucleic acid molecules during amplification reactions (U.S. Patent No. 9096893). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9096893

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Loading…