The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 04, 2015
Filed:
Jun. 14, 2011
Barbara Pui Chan, Hong Kong, HK;
Hoi Ling Wong, Hong Kong, HK;
Mei Yi Wong, Hong Kong, HK;
Godfrey Chi-fung Chan, Hong Kong, HK;
Zhen Fan Yang, Shanghai, CN;
Barbara Pui Chan, Hong Kong, HK;
Hoi Ling Wong, Hong Kong, HK;
Mei Yi Wong, Hong Kong, HK;
Godfrey Chi-Fung Chan, Hong Kong, HK;
Zhen Fan Yang, Shanghai, CN;
Versitech Limited, Hong Kong, HK;
Abstract
A method is provided to functionally select cells with enhanced characteristics relevant to cell engraftment, including both spontaneous migration and directional migration towards specific chemo-attractants. The cells are preferably undifferentiated cells, such as mesenchymal stem cells. The method involves entrapping or encapsulating the cells in a biomaterial barrier, optionally inducing cell migration, and selecting cells that migrated through the barrier. The cells selected by this method have better migratory activities and enhanced in vivo engraftment to injured tissues when they are supplemented systemically.