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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9096682 B1

PDFFull Text
Date of Patent:
Aug. 04, 2015

Filed:

Oct. 17, 2011

Peptides and uses

Applicants:

Mark Isalan, Barcelona, ES;

Mireia Garriga-canut, Barcelona, ES;

Inventors:

Mark Isalan, Barcelona, ES;

Mireia Garriga-Canut, Barcelona, ES;

Assignee:

FUNDACIO PRIVADA CENTRE DE REGULACIO GENOMICA, Barcelona, ES;

Attorneys:

Nixon Peabody LLP

David S. Resnick

Primary Examiner:

Karlheinz R Skowronek

Assistant Examiner:

Sergio Coffa

Int. Cl.
CPC ...
A61K 38/00 (2006.01); C07K 2/00 (2006.01); C07K 4/00 (2006.01); C07K 5/00 (2006.01); C07K 7/00 (2006.01); C07K 14/00 (2006.01); C07K 16/00 (2006.01); C07K 17/00 (2006.01); C07K 14/47 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4703 (2013.01); A61K 38/00 (2013.01);
Abstract

Disclosed herein are zinc finger peptides having at least 4 zinc finger domains, such as 6, 11, 12 or 18 zinc finger domains. The zinc finger peptides may be fused to effector domains for modulating gene expression. Zinc finger peptides of the invention are useful for targeting trinucleotide-repeat sequences in mutant genes and may have applications in gene therapy. The zinc finger peptides may have nucleic acid recognition sequences according to SEQ ID NO: 101. Also disclosed are methods for constructing poly-zinc finger peptides having arrays of at least 8 zinc finger domains, along with zinc finger frameworks that may be useful for selecting zinc finger peptides from libraries.

Find Patent Forward Citations

Isalan, Mark. (2015). Peptides and uses (U.S. Patent No. 9096682). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9096682

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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