The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 04, 2015

Filed:

Jun. 18, 2013
Applicant:

University of Pittsburgh—of the Commonwealth System of Higher Education, Pittsburgh, PA (US);

Inventors:

Soldano Ferrone, Boston, MA (US);

Xinhui Wang, Boston, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); C07K 16/18 (2006.01); C07K 16/30 (2006.01); G01N 33/574 (2006.01); A61K 45/06 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C07K 16/18 (2013.01); A61K 39/0011 (2013.01); A61K 45/06 (2013.01); C07K 16/3015 (2013.01); C07K 16/3053 (2013.01); G01N 33/57415 (2013.01); G01N 33/6854 (2013.01); A61K 2039/505 (2013.01); C07K 2316/96 (2013.01); C07K 2317/73 (2013.01);
Abstract

It is disclosed herein that condroitin sulfate proteoglycan 4 (CSPG4), also known as high molecular weight melanoma associated antigen, is overexpressed on basal breast carcinoma cells (BBC), specifically triple negative basal breast carcinoma cells (TNBC). Methods for detecting basal breast cancer in a subject are disclosed. Methods are also disclosed for inhibiting the growth of a basal breast cancer cell. These methods include contacting the basal breast cancer cell with an effective amount of an antibody that specifically binds CSPG4. Additional treatment methods, and the use of antibody panels, are also described herein.


Find Patent Forward Citations

Ferrone, Soldano. (2015). Monoclonal antibodies for cspg4 for the diagnosis and treatment of basal breast carcinoma (U.S. Patent No. 9096661). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9096661

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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