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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9096648 B1

PDFFull Text
Date of Patent:
Aug. 04, 2015

Filed:

Aug. 02, 2012

Methods of reducing level of one or more impurities in a sample during protein purification

Applicants:

Nanying Bian, Lexington, MA (US);

Christopher Gillespie, Shirley, MA (US);

Matthew T. Stone, Cambridge, MA (US);

Mikhail Kozlov, Lexington, MA (US);

Jie Chen, Stow, MA (US);

Martin Siwak, Topsfield, MA (US);

Inventors:

Nanying Bian, Lexington, MA (US);

Christopher Gillespie, Shirley, MA (US);

Matthew T. Stone, Cambridge, MA (US);

Mikhail Kozlov, Lexington, MA (US);

Jie Chen, Stow, MA (US);

Martin Siwak, Topsfield, MA (US);

Assignee:

EMD Millipore Corporation, Billerica, MA (US);

Attorney:

EMD Millipore Corporation

Primary Examiner:

Daniel E Kolker

Assistant Examiner:

James Rogers

Int. Cl.
CPC ...
A23J 1/00 (2006.01); C07K 1/00 (2006.01); C07K 14/00 (2006.01); C07K 17/00 (2006.01); C07K 1/36 (2006.01); B01D 15/36 (2006.01); B01J 20/282 (2006.01); C07K 1/16 (2006.01); C07K 1/20 (2006.01); B01D 15/12 (2006.01); B01J 39/26 (2006.01); B01J 41/20 (2006.01); B01J 43/00 (2006.01); B01J 47/04 (2006.01); C07K 16/00 (2006.01); B01D 15/18 (2006.01); B01D 15/38 (2006.01);
U.S. Cl.
CPC ...
C07K 1/36 (2013.01); B01D 15/125 (2013.01); B01D 15/362 (2013.01); B01D 15/363 (2013.01); B01J 20/282 (2013.01); B01J 39/26 (2013.01); B01J 41/20 (2013.01); B01J 43/00 (2013.01); B01J 47/04 (2013.01); C07K 1/16 (2013.01); C07K 1/20 (2013.01); C07K 16/00 (2013.01); B01D 15/1871 (2013.01); B01D 15/3809 (2013.01); C07K 2317/10 (2013.01);
Abstract

The present invention provides novel and improved protein purification processes which incorporate certain types of carbonaceous materials and result in effective and selective removal of certain undesirable impurities without adversely effecting the yield of the desired protein product.

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