The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 04, 2015

Filed:

Sep. 28, 2012
Applicant:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Inventors:

John W. Butcher, Berlin, MA (US);

David Witter, Norfolk, MA (US);

Christopher Dinsmore, Newton, MA (US);

June Kim, West Chester, PA (US);

John Hendrix, San Francisco, CA (US);

Raksha Archarya, Bedford, MA (US);

Sean P. Ahearn, Somerville, MA (US);

Joon Jung, Newton, MA (US);

Alexey Rivkin, Emeryville, CA (US);

Philip Jones, Houston, TX (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/10 (2006.01); A61K 31/437 (2006.01); C07D 471/04 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); C07D 519/00 (2013.01);
Abstract

The instant invention provides compounds of formula I which are JAK inhibitors, and as such are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.


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