The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 04, 2015
Filed:
Dec. 08, 2011
Daniel Holsworth, San Diego, CA (US);
JO Waaler, Oslo, NO;
Ondrej Machon, Prague, CZ;
Stefan Krauss, Eidsvoll verk, NO;
Andrey Edward Voronkov, Oslo, NO;
Daniel Holsworth, San Diego, CA (US);
Jo Waaler, Oslo, NO;
Ondrej Machon, Prague, CZ;
Stefan Krauss, Eidsvoll verk, NO;
Andrey Edward Voronkov, Oslo, NO;
OSLO UNIVERSITY HOSPITAL HF, , NO;
Abstract
The present invention relates to compounds of formula (I), to processes for their preparation, to pharmaceutical formulations containing such compounds and to their use in therapy: Such compounds find particular use in the treatment and/or prevention of conditions or diseases which are affected by over-activation of signaling in the Wnt pathway and increased presence of nuclear β-catenin. For example, these may be used in preventing and/or retarding proliferation of tumor cells and metastasis, for example carcinomas such as colon carcinomas.