The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 04, 2015
Filed:
Oct. 14, 2010
Gary E Keck, Salt Lake City, UT (US);
Matthew B Kraft, Salt Lake City, UT (US);
Anh P Truong, Burlingame, CA (US);
Carina C Sanchez, Somerville, MA (US);
Wei LI, Salt Lake City, UT (US);
Jonathan a Covel, San Diego, CA (US);
Dennie Welch, Lake Bluff, IL (US);
Yam Poudel, Salt Lake City, UT (US);
Gary E Keck, Salt Lake City, UT (US);
Matthew B Kraft, Salt Lake City, UT (US);
Anh P Truong, Burlingame, CA (US);
Carina C Sanchez, Somerville, MA (US);
Wei Li, Salt Lake City, UT (US);
Jonathan A Covel, San Diego, CA (US);
Dennie Welch, Lake Bluff, IL (US);
Yam Poudel, Salt Lake City, UT (US);
UNIVERSITY OF UTAH RESEARCH FOUNDATION, Salt Lake City, UT (US);
Abstract
Described herein are tricyclic macrolactones. The macrolactones have a high binding affinity for PKC. The compounds described herein can be used in a number of therapeutic applications including cancer and Alzheimer's prevention and treatment. The compounds described herein can also treat memory loss. Also described herein are methods for producing macrolactones. The methods permit the high-yield synthesis of macrolactones in fewer steps and with a higher degree of substitution and specificity.