The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 04, 2015

Filed:

Mar. 11, 2013
Applicants:

Jordan Tang, Oklahoma City, OK (US);

Xiangping Huang, Oklahoma City, OK (US);

Deborah Downs, Oklahoma City, OK (US);

Arun K. Ghosh, West Lafayette, IN (US);

Inventors:

Jordan Tang, Oklahoma City, OK (US);

Xiangping Huang, Oklahoma City, OK (US);

Deborah Downs, Oklahoma City, OK (US);

Arun K. Ghosh, West Lafayette, IN (US);

Assignees:

Oklahoma Medical Research Foundation, Oklahoma City, OK (US);

Purdue Research Foundation, West Lafayette, IN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/166 (2006.01); A61K 31/4965 (2006.01); A61K 38/05 (2006.01); C07D 239/84 (2006.01); C07D 403/12 (2006.01); C07D 417/12 (2006.01); C07D 413/12 (2006.01); C07D 513/04 (2006.01); C07D 241/04 (2006.01); C07K 5/02 (2006.01); C07C 311/08 (2006.01); A61K 31/495 (2006.01); A61K 31/18 (2006.01);
U.S. Cl.
CPC ...
C07D 239/84 (2013.01); A61K 31/166 (2013.01); A61K 31/18 (2013.01); A61K 31/495 (2013.01); A61K 38/05 (2013.01); C07C 311/08 (2013.01); C07D 241/04 (2013.01); C07D 403/12 (2013.01); C07D 413/12 (2013.01); C07D 417/12 (2013.01); C07D 513/04 (2013.01); C07K 5/0207 (2013.01);
Abstract

Proteases such as memapsin-1 are import enzymes, playing roles in a variety of diseases including diabetes. The inventors have developed inhibitors of memapsin 1 and methods of use therefore in the treatment of disease.


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