The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 04, 2015

Filed:

Aug. 29, 2013
Applicant:

Zalicus Pharmaceuticals, Ltd., Boston, MA (US);

Inventors:

Hassan Pajouhesh, West Vancouver, CA;

Ramesh Kaul, Burnaby, CA;

Yanbing Ding, Richmond, CA;

Yongbao Zhu, Langley, CA;

Lingyun Zhang, Vancouver, CA;

Nagasree Chakka, Cambridge, MA (US);

Michael Edward Grimwood, North Vancouver, CA;

Jason Tan, Richmond, CA;

Yuanxi Zhou, Richmond, CA;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 211/28 (2006.01); C07D 405/12 (2006.01); C07D 401/06 (2006.01); C07D 211/62 (2006.01); C07D 409/12 (2006.01); C07D 405/06 (2006.01); C07D 417/12 (2006.01); C07D 211/26 (2006.01); C07D 401/12 (2006.01); C07D 211/66 (2006.01); C07D 405/14 (2006.01); C07D 211/46 (2006.01); C07D 211/38 (2006.01); C07D 413/12 (2006.01); A61K 31/445 (2006.01); A61K 31/454 (2006.01);
U.S. Cl.
CPC ...
C07D 211/28 (2013.01); A61K 31/445 (2013.01); A61K 31/454 (2013.01); C07D 211/26 (2013.01); C07D 211/38 (2013.01); C07D 211/46 (2013.01); C07D 211/62 (2013.01); C07D 211/66 (2013.01); C07D 401/06 (2013.01); C07D 401/12 (2013.01); C07D 405/06 (2013.01); C07D 405/12 (2013.01); C07D 405/14 (2013.01); C07D 409/12 (2013.01); C07D 413/12 (2013.01); C07D 417/12 (2013.01);
Abstract

Methods and compounds effective in ameliorating conditions characterized by unwanted calcium channel activity, particularly unwanted T-type calcium channel activity are disclosed. Specifically, a series of compounds containing N-piperidinyl acetamide derivatives as shown in formula (1).


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