The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 04, 2015

Filed:

May. 21, 2014
Applicant:

The Regents of the University of Michigan, Ann Arbor, MI (US);

Inventors:

Daniel A. Lawrence, Ann Arbor, MI (US);

Dudley Strickland, Brookville, MD (US);

Jacqueline Cale, Minneapolis, MN (US);

Enming Joe Su, Ann Arbor, MI (US);

Cory Emal, Ann Arbor, MI (US);

Mark Warnock, Brighton, MI (US);

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 311/29 (2006.01); C07C 69/88 (2006.01); C07C 271/22 (2006.01); C07H 13/08 (2006.01); G01N 33/92 (2006.01);
U.S. Cl.
CPC ...
C07C 311/29 (2013.01); C07C 69/88 (2013.01); C07C 271/22 (2013.01); C07H 13/08 (2013.01); G01N 33/92 (2013.01); C07C 2101/14 (2013.01); G01N 2333/8132 (2013.01); G01N 2500/02 (2013.01);
Abstract

The invention relates to plasminogen activator-1 (PAI-1) inhibitor compounds and uses thereof in the treatment of any disease or condition associated with elevated PAI-1. The invention includes, but is not limited to, the use of such compounds to modulate lipid metabolism and treat conditions associated with elevated PAI-1, cholesterol, or lipid levels.


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