The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 04, 2015

Filed:

Mar. 14, 2013
Applicant:

University of Massachusetts, Boston, MA (US);

Inventor:

Alexei A. Bogdanov, Westborough, MA (US);

Assignee:

University of Massachusetts, Boston, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/48 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48315 (2013.01); A61K 47/48884 (2013.01); Y10T 428/2998 (2015.01);
Abstract

There is provided a method of preparing nanoparticles and novel nanoparticles. The nanoparticle preparation comprises the generation of a mixture comprising a plurality of metal-containing compounds and a copolymer of a polyethylene glycol and an amine-containing polyamino acid such as polylysine where a metal core and polymer shell nanoparticle is formed. The novel nanoparticles have a metallic core and a graft copolymer shell of polyethylene glycol and an amine-containing polyamino acid where the shell least partially surrounds the metallic core and is non-ionically bound to the metallic core via metal-amine bonds.


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