The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 04, 2015

Filed:

Nov. 30, 2010
Applicants:

Jeffrey N. Miner, San Diego, CA (US);

Mark S. Chapman, San Diego, CA (US);

Barry Quart, Encinitas, CA (US);

Alex Adjei, Williamsville, NY (US);

Chunrong Yu, Williamsville, NY (US);

Inventors:

Jeffrey N. Miner, San Diego, CA (US);

Mark S. Chapman, San Diego, CA (US);

Barry Quart, Encinitas, CA (US);

Alex Adjei, Williamsville, NY (US);

Chunrong Yu, Williamsville, NY (US);

Assignee:

Ardea Biosciences, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4439 (2006.01); A61K 31/18 (2006.01); A61K 31/4412 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4439 (2013.01); A61K 31/18 (2013.01); A61K 31/4412 (2013.01); A61K 45/06 (2013.01);
Abstract

This invention concerns combinations of inhibitors of MEK, Raf protein kinases, and other kinases including VEGFR1-3 and PDGFR-β. This invention also concerns pharmaceutical compositions comprising the compounds described herein and methods of use of the compounds and compositions described herein, including the use in the treatment and/or prevention of cancer and other hyperproliferative disorders.


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