The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 04, 2015

Filed:

Sep. 26, 2008
Applicants:

Mark Berninger, Gaithersburg, MD (US);

Puthupparampil Scaria, Montgomery Village, MD (US);

Inventors:

Mark Berninger, Gaithersburg, MD (US);

Puthupparampil Scaria, Montgomery Village, MD (US);

Assignee:

Other;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/07 (2006.01); A61K 39/00 (2006.01); A61K 39/385 (2006.01); A61K 47/00 (2006.01); A01N 63/00 (2006.01); A61K 39/39 (2006.01);
U.S. Cl.
CPC ...
A61K 39/39 (2013.01); A61K 2039/55555 (2013.01);
Abstract

Polyelectrolyte nanoparticle compositions for biomedical applications are provided comprising at least two carrier domains comprising multivalent ionic domains and an agent exhibiting biological activity when contained within the nanoparticle or on the nanoparticle surface. The multivalent ionic domains may be contained in two separate molecules or in separate but linked domains of a single molecule. The nanoparticle optionally can further comprise an exposed targeting ligand and/or protective surface. The nanoparticle can be contacted to cells or administered directly to an animal for biomedical applications including therapeutics and immune response. The nanoparticle may alternatively be comprised of a carrier material capable of delivering various medically important antigens as vaccine.


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