The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 04, 2015
Filed:
Jun. 20, 2008
Applicants:
Joost Schymkowitz, Meensel-Kiezegem, BE;
Frederic Rousseau, Groot-Bijgaarden, BE;
Inventors:
Joost Schymkowitz, Meensel-Kiezegem, BE;
Frederic Rousseau, Groot-Bijgaarden, BE;
Assignees:
VIB VZW, Zwijnaarde, BE;
VRIJE UNIVERSITEIT BRUSSEL, Brussels, BE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 38/16 (2006.01); A61K 38/10 (2006.01); A61K 38/08 (2006.01); A61K 38/18 (2006.01); A61K 47/48 (2006.01); C12N 15/82 (2006.01);
U.S. Cl.
CPC ...
A61K 38/1866 (2013.01); A61K 38/16 (2013.01); A61K 47/48246 (2013.01); C12N 15/8216 (2013.01); C12N 15/8257 (2013.01); C07K 2319/735 (2013.01);
Abstract
The invention belongs to the field of functional proteomics and, more particularly, to the field of protein aggregation. Described are methods for interfering with the function of a target protein and uses a non-naturally, user-designed molecule, designated as interferor, that has a specificity for a target protein and that induces aggregation upon contact with the target protein. The invention also discloses such interferer molecules and their use in therapeutic applications.