The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 04, 2015

Filed:

Sep. 09, 2011
Applicants:

Olaf Schneewind, Chicago, IL (US);

Alice G. Cheng, Boston, MA (US);

Dominique M. Missiakas, Chicago, IL (US);

Hwan Keun Kim, Naperville, IL (US);

Hye-young Kim, Rancho Cucamonga, CA (US);

Inventors:

Olaf Schneewind, Chicago, IL (US);

Alice G. Cheng, Boston, MA (US);

Dominique M. Missiakas, Chicago, IL (US);

Hwan Keun Kim, Naperville, IL (US);

Hye-Young Kim, Rancho Cucamonga, CA (US);

Assignee:

The University of Chicago, Chicago, IL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/02 (2006.01); A61K 39/09 (2006.01); C07K 1/00 (2006.01); A61K 39/085 (2006.01); C07K 14/31 (2006.01);
U.S. Cl.
CPC ...
A61K 39/085 (2013.01); C07K 14/31 (2013.01); A61K 2039/522 (2013.01); A61K 2039/55566 (2013.01);
Abstract

The present invention concerns methods and compositions for treating or preventing a bacterial infection, particularly infection by abacterium. The invention provides methods and compositions for stimulating an immune response against the bacteria. In certain embodiments, the methods and compositions involve a non-toxigenic Protein A (SpA) variant. In some embodiments, the methods and compositions involve SdrD, ClfA, and/or FnbpB polypeptides.


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