The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 04, 2015

Filed:

Aug. 24, 2010
Applicants:

Changjoon Justin Lee, Seoul, KR;

Soo-jung Lee, Seoul, KR;

Bo-eun Yoon, Yongin-si, KR;

Inventors:

Changjoon Justin Lee, Seoul, KR;

Soo-Jung Lee, Seoul, KR;

Bo-Eun Yoon, Yongin-si, KR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 49/00 (2006.01); A61P 25/00 (2006.01); A61P 25/28 (2006.01); A61P 25/32 (2006.01); A61P 25/08 (2006.01); G01R 27/28 (2006.01); A61K 31/00 (2006.01); A61K 31/185 (2006.01); A61K 31/196 (2006.01); A61K 31/455 (2006.01); A61K 31/7105 (2006.01); A61K 31/713 (2006.01); A61K 38/04 (2006.01); A61K 38/08 (2006.01); G01N 33/94 (2006.01);
U.S. Cl.
CPC ...
A61K 31/00 (2013.01); A61K 31/185 (2013.01); A61K 31/196 (2013.01); A61K 31/455 (2013.01); A61K 31/713 (2013.01); A61K 31/7105 (2013.01); A61K 38/043 (2013.01); A61K 38/08 (2013.01); G01N 33/9426 (2013.01); G01N 2500/10 (2013.01);
Abstract

A GABA (gamma-aminobutyric acid) release-inhibiting agent in the cerebellum and a composition for treating pathological symptoms caused by over-release of GABA in the cerebellum, each comprising a Bestrophin 1 (Best1) channel inhibitor as an active ingredient; a GABA release-promoting agent in the cerebellum and a composition for treating pathological symptoms caused by the deficit of GABA in the cerebellum, each comprising a Best1 channel activator as an active ingredient; and a method for screening a GABA release-regulating agent in the cerebellum, which uses Best1 channel as target, are provided.


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